Beggars in Spain, the first book, is a beautiful, painful exploration of prejudice, the belief in rule of law and medical/biological ethics. It is also an exploration of an uncommon concept: economic ethics...as well as simply being the story of a woman carefully designed to superiority and her efforts to live productively in a world that hates & fears her.
The story is poignant, yet remarkably uncluttered. It shows us a very believable picture of what the future could look like, under certain circumstances, and it questions scientific advancement without ethics. Well worth the read.
I don't know why I never ran across Nancy Kress before; she's an excellent writer, and an excellent thinker, and a compelling story-teller. Based on what I've read so far, I highly recommend her work.